Anti-GPSM1 Antibody
Boster Bio Anti-GPSM1 Antibody catalog # A04971-1. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate (GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein (p-CREB) .
Synonyms
G-protein-signaling modulator 1; AGS3; Activator of G-protein signaling 3
Gene Name
GPSM1
UniProt
Q86YR5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human GPSM1 recombinant protein (Position: A3-E298) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
G protein signaling modulator 1
Protein Name
G-protein-signaling modulator 1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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