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Anti-IRK8 KCNJ8 Antibody

Boster Bio Anti-IRK8 KCNJ8 Antibody catalog # A04950. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ATP-sensitive inward rectifier potassium channel 8; Inward rectifier K (+) channel Kir6.1; Potassium channel, inwardly rectifying subfamily J member 8; uKATP-1; KCNJ8

Gene Name

KCNJ8

UniProt

Q15842

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 50-130

Clonality

Polyclonal

Tissue Specificity

Predominantly detected in fetal and adult heart.

Applications

WB, ELISA

Purification

IRK8 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

47968 MW

Gene Name Synonym

ATP-sensitive inward rectifier potassium channel 8

Subcellular Location

Membrane; Multi-pass membrane protein .

Protein Name

ATP-sensitive inward rectifier potassium channel 8

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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