Anti-HERPUD1 Antibody
Boster Bio Anti-HERPUD1 Antibody catalog # A04908. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; Methyl methanesulfonate (MMF) -inducible fragment protein 1; HERPUD1; HERP, KIAA0025, MIF1
Gene Name
HERPUD1
UniProt
Q15011
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full length Human HERPUD1.
Clonality
Polyclonal
Tissue Specificity
Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
43720 MW
Gene Name Synonym
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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