Anti-Protein lifeguard 2 FAIM2 Antibody
Boster Bio Anti-Protein lifeguard 2 FAIM2 Antibody catalog # A04900. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2; FAIM2; KIAA0950, LFG, LFG2, NMP35, TMBIM2
Gene Name
FAIM2
UniProt
Q9BWQ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human FAIM2.
Tissue Specificity
Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level) . Widely expressed. Expressed at high levels in the brain especially in the hippocampus. .
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
35110 MW
Gene Name Synonym
Protein lifeguard 2
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane .
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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