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Anti-MAP3K4/Mekk4 Antibody

Boster Bio Anti-MAP3K4/Mekk4 Antibody (Catalog# A04842) . Tested in IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

MAP3K4; KIAA0213; MAPKKK4; MEKK4; MTK1; Mitogen-activated protein kinase kinase kinase 4; MAP three kinase 1; MAPK/ERK kinase kinase 4; MEK kinase 4; MEKK 4

Gene Name

MAP3K4

UniProt

Q9Y6R4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human MAP3K4. Immunogen sequence location: 1281-1330

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.

Applications

IHC, ICC, IF, ELISA

Field of Research

MAPK Pathway, Neurogenesis, Neurology Process, Neuroscience, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Tyrosine Kinases

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

181685 MW

Gene Name Synonym

Mitogen-activated protein kinase kinase kinase 4

Subcellular Location

Cytoplasm, perinuclear region. Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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