Anti-UBR4 Antibody
Boster Bio Anti-UBR4 Antibody catalog # A04824-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4), also named P600, is an E3 ligase that can bind N-end rule substrates. UBR4-deficient mice die during embryogenesis and exhibit pleiotropic abnormalities (PMID: 23431188) . UBR4 plays a role in membrane morphogenesis and extracellular matrix-mediated cell survival and signaling, human papillomavirus (HPV) E7-mediated cellular immortalization, and migration and development of neurons (PMID: 33658508, 25084275) . The full-length UBR4 protein has a predicted size of ~570 kDa.
Synonyms
RBAF600; p600; N-recognin-4; EC:2.3.2.27; E3 ubiquitin-protein ligase UBR4
Gene Name
UBR4
UniProt
Q5T4S7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human UBR4 recombinant protein (Position: T453-S797) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Ubiquitin protein ligase E3 component n-recognin 4
Protein Name
E3 ubiquitin-protein ligase UBR4
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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