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Anti-ACTR-IIA (H59) ACVR2A Antibody

Boster Bio Anti-ACTR-IIA (H59) ACVR2A Antibody catalog # A04770. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Activin receptor type-2A;2.7.11.30; Activin receptor type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2

Gene Name

ACVR2A

UniProt

P27037

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 30-80 of Human ACTR-IIA.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

57848 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Activin receptor type-2A

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Activin receptor type-2A

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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