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Anti-SAE1 Antibody

Boster Bio Anti-SAE1 Antibody catalog # A04753. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SUMO-activating enzyme subunit 1, N-terminally processed; SAE1; AOS1, SUA1, UBLE1A

Gene Name

SAE1

UniProt

Q9UBE0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human AOS1. AA range:221-270

Clonality

Polyclonal

Tissue Specificity

Expression level increases during S phase and drops in G2 phase (at protein level) .

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

38450 MW

Gene Name Synonym

SUMO-activating enzyme subunit 1

Subcellular Location

Nucleus

Protein Name

SUMO-activating enzyme subunit 1

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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