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Anti-SMCHD1 Antibody

Boster Bio Anti-SMCHD1 Antibody catalog # A04751. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Structural maintenance of chromosomes flexible hinge domain-containing protein 1; SMC hinge domain-containing protein 1; SMCHD1; KIAA0650

Gene Name

SMCHD1

UniProt

A6NHR9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human SMCHD1.

Clonality

Polyclonal

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity) . Required for DUX4 silencing in somatic cells (PubMed:23143600) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

226374 MW

Gene Name Synonym

Structural maintenance of chromosomes flexible hinge domain-containing protein 1

Subcellular Location

Chromosome

Protein Name

Structural maintenance of chromosomes flexible hinge domain-containing protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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