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Anti-TEM1/CD248 Antibody

Boster Bio Anti-TEM1/CD248 Antibody catalog # A04735-3. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

TEM1 (Tumor endothelial marker 1), also named as CD248, Endosialin and CD164L1, is a C-type lectin-like domain (CTLD) containing type I transmembrane glycoprotein. It is now considered to be a highly selective marker for activated perivascular and stromal cells, detected in most cancers and at least some inflammatory disorders. CD248 plays a role in tumor angiogenesis. It is a potential diagnostic tool and therapeutic target of inflammatory and malignant disease. Two isoforms of human TEM1 exist. The calculated molecular weights of the two isoforms are 81 kDa and 46 kDa, respectively. Native TEM1 can be glycosylated, and the glycosylated form has a larger apparent molecular weight than 81 kDa.

Gene Name

CD248

UniProt

Q9HCU0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human TEM1/CD248 recombinant protein (Position: A23-M398) .

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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