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Anti-SLC29A2 Antibody

Boster Bio Anti-SLC29A2 Antibody (Catalog # A04718) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Product Specifications

Background

SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2) . SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3) . As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4) .

Synonyms

Solute carrier family 29 member 2, Equilibrative nucleoside transporter 2, ENT2, DER12, HNP36

Gene Name

SLC29A2

UniProt

Q14542

Host

Rabbit

Reactivity

Human

Cross Reactivity

SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins.

Immunogen

SLC29A2 antibody was raised against a 19 amino acid peptide near the center of human SLC29A2. The immunogen is located within amino acids 250 - 300 of SLC29A2.

Clonality

Polyclonal

Tissue Specificity

Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Cancer, Homeostasis

Purification

SLC29A2 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.

Storage Conditions

SLC29A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

50113 MW

Gene Name Synonym

Solute carrier family 29 (equilibrative nucleoside transporter), member 2

Subcellular Location

Basolateral cell membrane

Prediction Reactivity

Rat

Protein Name

Solute carrier family 29 (equilibrative nucleoside transporter), member 2

Isotype

IgG

Contents

SLC29A2 antibody is supplied in PBS containing 0.02% sodium azide.

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