Anti-Transcription factor MafG MAFG Antibody
Boster Bio Anti-Transcription factor MafG MAFG Antibody catalog # A04636. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Transcription factor MafG; V-maf musculoaponeurotic fibrosarcoma oncogene homolog G; hMAF; MAFG
Gene Name
MAFG
UniProt
O15525
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human MAFG
Clonality
Polyclonal
Tissue Specificity
Highly expressed in skeletal muscle. Also expressed in heart and brain.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:11154691) . However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691) . Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed:11154691) . Transcription factor, component of erythroid-specific transcription factor NFE2L2 (PubMed:11154691) . Activates globin gene expression when associated with NFE2L2 (PubMed:11154691) . May be involved in signal transduction of extracellular H (+) (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
17850 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Transcription factor MafG
Subcellular Location
Nucleus
Protein Name
Transcription factor MafG
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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