Anti-SPDEF Antibody
Boster Bio Anti-SPDEF Antibody catalog # A04625. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
SAM pointed domain-containing Ets transcription factor; Prostate epithelium-specific Ets transcription factor; Prostate-specific Ets; Prostate-derived Ets factor; SPDEF; PDEF, PSE
Gene Name
SPDEF
UniProt
O95238
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human SPDEF (NP_036523.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT- 3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
37518 MW
Gene Name Synonym
SAM pointed domain-containing Ets transcription factor
Subcellular Location
Nucleus .
Protein Name
SAM pointed domain-containing Ets transcription factor
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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