Anti-TORC3 CRTC3 Monoclonal Antibody
Boster Bio Anti-TORC3 CRTC3 Monoclonal Antibody catalog # A04568. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Monkey.
Product Specifications
Synonyms
CREB-regulated transcription coactivator 3; Transducer of regulated cAMP response element-binding protein 3; TORC-3; Transducer of CREB protein 3; CRTC3; TORC3
Gene Name
CRTC3
UniProt
Q6UUV7
Host
Mouse
Reactivity
Human, Monkey
Immunogen
Purified recombinant fragment of human TORC3 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 5G9
Tissue Specificity
Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. .
Applications
WB, IHC, IF, ELISA
Purification
Affinity purification
Sensitivity
>5000 cells
Concentration
1 mg/mL
Form
Liquid
Function
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
66959 MW
Gene Name Synonym
CREB-regulated transcription coactivator 3
Subcellular Location
Nucleus . Cytoplasm . Appears to be mainly nuclear. .
Isotype
IgG1
Contents
Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
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