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Anti-Dyrk1B Antibody

Boster Bio Anti-Dyrk1B Antibody catalog # A04556. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Dual specificity tyrosine-phosphorylation-regulated kinase 1B;2.7.12.1; Minibrain-related kinase; Mirk protein kinase; DYRK1B; MIRK

Gene Name

DYRK1B

UniProt

Q9Y463

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380

Clonality

Polyclonal

Tissue Specificity

Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines.

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

69198 MW

Gene Name Synonym

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

Subcellular Location

Nucleus.

Protein Name

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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