Anti-SLC47A1 Antibody
Boster Bio Anti-SLC47A1 Antibody catalog # A04529. Tested in WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Multidrug and toxin extrusion protein 1; MATE-1; hMATE-1; Solute carrier family 47 member 1; SLC47A1; MATE1
Gene Name
SLC47A1
UniProt
Q96FL8
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant protein of human SLC47A1
Clonality
Polyclonal
Tissue Specificity
Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent) . Able to transport paraquat (PQ or N, N-dimethyl-4-4'-bipiridinium) ; a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
61922 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Multidrug and toxin extrusion protein 1
Subcellular Location
Cell membrane
Protein Name
Multidrug and toxin extrusion protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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