Anti-La-related protein 1 LARP1 Antibody
Boster Bio Anti-La-related protein 1 LARP1 Antibody catalog # A04488. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
La-related protein 1; La ribonucleoprotein domain family member 1; LARP1; KIAA0731, LARP
Gene Name
LARP1
UniProt
Q6PKG0
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human LARP1 (Q6PKG0) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex (PubMed:24532714, PubMed:25940091) . Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery (PubMed:24532714, PubMed:25940091, PubMed:26206669) . Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation (PubMed:20430826, PubMed:25940091) . Positively regulates the replication of dengue virus (DENV) (PubMed:26735137) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
123510 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
La-related protein 1
Subcellular Location
Cytoplasm
Protein Name
La-related protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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