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Anti-KIF4A Antibody

Boster Bio Anti-KIF4A Antibody catalog # A04486. Tested in WB, ELISA, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Chromosome-associated kinesin KIF4A; Chromokinesin-A; KIF4A; KIF4

Gene Name

KIF4A

UniProt

O95239

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human KIF4A. AA range:1171-1220

Clonality

Polyclonal

Tissue Specificity

Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.

Applications

WB, ELISA, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

139881 MW

Gene Name Synonym

Chromosome-associated kinesin KIF4A

Subcellular Location

Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.

Protein Name

Chromosome-associated kinesin KIF4A

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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