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Anti-FUT8 Antibody (Center)

Boster Bio Anti-FUT8 Antibody (Center) (Catalog # A04453) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified.

Synonyms

Alpha- (1,6) -fucosyltransferase, Alpha1-6FucT, Fucosyltransferase 8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase, GDP-fucose--glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, FUT8

Gene Name

FUT8

UniProt

Q9BYC5

Host

Rabbit

Reactivity

Human

Immunogen

This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8.

Clonality

Polyclonal

Applications

IHC-P, WB

Field of Research

Cancer, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

66516 Da

Subcellular Location

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein Note=Membrane-bound form in trans cisternae of Golgi.

Prediction Reactivity

Bovine, Mouse, Pig, Rat

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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