Anti-DEFB4 Antibody
Boster Bio Anti-DEFB4 Antibody catalog # A04398. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Beta-defensin 4A; Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1; DEFB4A; DEFB102, DEFB2, DEFB4; DEFB4B
Gene Name
DEFB4A
UniProt
O15263
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human DEFB4.
Clonality
Polyclonal
Tissue Specificity
Expressed in the skin and respiratory tract.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
7038 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Beta-defensin 4A
Subcellular Location
Secreted.
Protein Name
Beta-defensin 4A
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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