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Anti-CREM (I106) Antibody

Boster Bio Anti-CREM (I106) Antibody catalog # A04379. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CAMP-responsive element modulator ; Inducible cAMP early repressor; ICER; CREM

Gene Name

CREM

UniProt

Q03060

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 80-130 of Human CREM.

Clonality

Polyclonal

Tissue Specificity

Expressed in testes (round spermatids) (at protein level) . Isoform 14 is the major activator form in testes.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

37006 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

CAMP-responsive element modulator

Subcellular Location

Nucleus.

Protein Name

CAMP-responsive element modulator

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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