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Anti-HMGCS2 Antibody

Boster Bio Anti-HMGCS2 Antibody catalog # A04371. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Hydroxymethylglutaryl-CoA synthase, mitochondrial; HMG-CoA synthase;2.3.3.10;3-hydroxy-3-methylglutaryl coenzyme A synthase; HMGCS2

Gene Name

HMGCS2

UniProt

P54868

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human HMGCS2 (NP_005509.1) .

Clonality

Polyclonal

Tissue Specificity

Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas. Very low expression in heart and skeletal muscle. Not detected in brain. The relative expression of isoform 3 (at mRNA level) is highest in heart (70%) and skeletal muscle (60%) .

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

56635 MW

Gene Name Synonym

Hydroxymethylglutaryl-CoA synthase, mitochondrial

Subcellular Location

Mitochondrion.

Protein Name

Hydroxymethylglutaryl-CoA synthase, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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