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Anti-WBSCR11 (K94) GTF2IRD1 Antibody

Boster Bio Anti-WBSCR11 (K94) GTF2IRD1 Antibody catalog # A04254. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

General transcription factor II-I repeat domain-containing protein 1; GTF2I repeat domain-containing protein 1; General transcription factor III; MusTRD1/BEN; Muscle TFII-I repeat domain-containing protein 1; Slow-muscle-fiber enhancer-binding protein; USE B1-binding protein; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein; GTF2IRD1; CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12

Gene Name

GTF2IRD1

UniProt

Q9UHL9

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide, corresponding to amino acids 63-112 of Human WBSCR11.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1) . Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

106057 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

General transcription factor II-I repeat domain-containing protein 1

Subcellular Location

Nucleus.

Protein Name

General transcription factor II-I repeat domain-containing protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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