Anti-TMPRSS3 (F440) Antibody
Boster Bio Anti-TMPRSS3 (F440) Antibody catalog # A04164. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transmembrane protease serine 3;3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; TMPRSS3; ECHOS1, TADG12; UNQ323/PRO382
Gene Name
TMPRSS3
UniProt
P57727
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 420-460 of Human TMPRSS3.
Clonality
Polyclonal
Tissue Specificity
Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity) . Activates ENaC (in vitro) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
49405 MW
Gene Name Synonym
Transmembrane protease serine 3
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Transmembrane protease serine 3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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