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Anti-TMPRSS3 (F440) Antibody

Boster Bio Anti-TMPRSS3 (F440) Antibody catalog # A04164. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Transmembrane protease serine 3;3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; TMPRSS3; ECHOS1, TADG12; UNQ323/PRO382

Gene Name

TMPRSS3

UniProt

P57727

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 420-460 of Human TMPRSS3.

Clonality

Polyclonal

Tissue Specificity

Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

Applications

IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity) . Activates ENaC (in vitro) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

49405 MW

Gene Name Synonym

Transmembrane protease serine 3

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Transmembrane protease serine 3

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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