Anti-SLC22A8 Antibody
Boster Bio Anti-SLC22A8 Antibody catalog # A04087. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Solute carrier family 22 member 8; Organic anion transporter 3; hOAT3; SLC22A8; OAT3
Gene Name
SLC22A8
UniProt
Q8TCC7
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human SLC22A8.
Clonality
Polyclonal
Tissue Specificity
Expressed in kidney.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
59856 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Solute carrier family 22 member 8
Subcellular Location
Basolateral cell membrane ; Multi-pass membrane protein . Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity) . .
Protein Name
Solute carrier family 22 member 8
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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