Anti-CYP51A1 Antibody (Center)

Boster Bio Anti-CYP51A1 Antibody (Center) (Catalog # A04032-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol.

Synonyms

Lanosterol 14-alpha demethylase, LDM, CYPLI, Cytochrome P450 51A1, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase, CYP51A1, CYP51

Gene Name

CYP51A1

UniProt

Q16850

Host

Rabbit

Reactivity

Human

Immunogen

This CYP51A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human CYP51A1.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung

Applications

WB, Flow Cytometry, IHC-P

Field of Research

Cardiovascular, Metabolism, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

57278 Da

Subcellular Location

Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q64654}; Single-pass membrane protein. Microsome membrane {ECO:0000250|UniProtKB:Q64654}; Single-pass membrane protein