Anti-PQBP1 Antibody
Boster Bio Anti-PQBP1 Antibody catalog # A04031-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
PQBP1 (Polyglutamine-binding protein 1) is also named as NPW38 and JM26. PQBP1 senses extrinsic tau 3R/4R proteins by direct interaction and triggers an innate immune response by activating a cyclic GMP-AMP synthase (cGAS) -Stimulator of interferon genes (STING) pathway (PMID: 34782623) . PQBP1 is abundantly expressed in the central nervous system during development. PQBP1 is a component of the precatalytic spliceosome (B complex) that is involved in splicing. PQBP1 was predominantly localized in the cell nucleus. PQBP1 is overexpressed in various cancer types including breast cancer, colon cancer, and glioblastoma (PMID: 38342602) .
Synonyms
PQBP-1; Polyglutamine-binding protein 1; Polyglutamine tract-binding protein 1; Npw38
Gene Name
PQBP1
UniProt
O60828
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human PQBP1 recombinant protein (Position: L3-Q263) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Polyglutamine binding protein 1
Protein Name
Polyglutamine-binding protein 1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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