Anti-GGA2 Antibody
Boster Bio Anti-GGA2 Antibody catalog # A04016. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
ADP-ribosylation factor-binding protein GGA2; Gamma-adaptin-related protein 2; Golgi-localized, gamma ear-containing, ARF-binding protein 2; VHS domain and ear domain of gamma-adaptin; Vear; GGA2; KIAA1080
Gene Name
GGA2
UniProt
Q9UJY4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human GGA2 (NP_055859.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif (PubMed:10747088) . Mediates export of the GPCR receptor ADRA2B to the cell surface (PubMed:27901063) . Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network (PubMed:15615712) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
67150 MW
Gene Name Synonym
ADP-ribosylation factor-binding protein GGA2
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Protein Name
ADP-ribosylation factor-binding protein GGA2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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