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Anti-Transcription factor SOX-18 SOX18 Antibody

Boster Bio Anti-Transcription factor SOX-18 SOX18 Antibody (Catalog # A04004) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2) . SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3) . SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4) . Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5) .

Synonyms

HLTS, Transcription factor SOX-18

Gene Name

SOX18

UniProt

P35713

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

SOX18 antibody is human, mouse and rat reactive. SOX18 is predicted to not cross-react with other SOX proteins.

Immunogen

SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18. The immunogen is located within amino acids 40 - 90 of SOX18.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Stem Cells

Purification

SOX18 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site. .

Storage Conditions

SOX18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

40891 MW

Gene Name Synonym

RY (sex determining region Y) -box 18

Subcellular Location

Nucleus

Protein Name

RY (sex determining region Y) -box 18

Isotype

IgG

Contents

SOX18 antibody is supplied in PBS containing 0.02% sodium azide.

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