Anti-UBE2D2 Antibody
Boster Bio Anti-UBE2D2 Antibody catalog # A03971. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ubiquitin-conjugating enzyme E2 D2;2.3.2.23
Gene Name
UBE2D2
UniProt
P62837
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 102-147 of Human UBE2D2.
Clonality
Polyclonal
Applications
WB, ICC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
16735 MW
Gene Name Synonym
Ubiquitin-conjugating enzyme E2 D2
Protein Name
Ubiquitin-conjugating enzyme E2 D2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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