Anti-Nuclear pore glycoprotein p62 NUP62 Antibody
Boster Bio Anti-Nuclear pore glycoprotein p62 NUP62 Antibody catalog # A03950. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Nuclear pore glycoprotein p62;62 kDa nucleoporin; Nucleoporin Nup62; NUP62
Gene Name
NUP62
UniProt
P37198
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human NUP62 (NP_036478.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Essential component of the nuclear pore complex (PubMed:1915414) . The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414) . The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630) . Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630) . It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
53255 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Nuclear pore glycoprotein p62
Subcellular Location
Nucleus, nuclear pore complex
Protein Name
Nuclear pore glycoprotein p62
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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