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Anti-Nuclear pore glycoprotein p62 NUP62 Antibody

Boster Bio Anti-Nuclear pore glycoprotein p62 NUP62 Antibody catalog # A03950. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Nuclear pore glycoprotein p62;62 kDa nucleoporin; Nucleoporin Nup62; NUP62

Gene Name

NUP62

UniProt

P37198

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human NUP62 (NP_036478.2) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Essential component of the nuclear pore complex (PubMed:1915414) . The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414) . The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630) . Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630) . It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

53255 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Nuclear pore glycoprotein p62

Subcellular Location

Nucleus, nuclear pore complex

Protein Name

Nuclear pore glycoprotein p62

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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