Anti-SYNCRIP Antibody
Boster Bio Anti-SYNCRIP Antibody catalog # A03946-2. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
Synaptotagmin-binding, cytoplasmic RNA-interacting protein (SYNCRIP), also identified as hnRNP Q, involves in mRNA processing mechanisms. It's component of the CRD-mediated complex that promotes MYC mRNA stability. Also it is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly (A) and poly (U) RNA sequences. As previously reported, the 65 and 74 kDa proteins corresponded to two isoforms of SYNCRIP produced from alternatively spliced mRNAs (PMID: 15340051) .
Synonyms
HNRPQ1; HNRPQ; hnRNP Q; GRY-RBP; GRY RBP
Gene Name
SYNCRIP
UniProt
O60506
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human SYNCRIP recombinant protein (Position: T3-G348) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Synaptotagmin binding cytoplasmic RNA interacting protein
Protein Name
Heterogeneous nuclear ribonucleoprotein Q
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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