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Anti-14-3-3 Theta / Tau (phospho-S232) YWHAQ Antibody

Boster Bio Anti-14-3-3 Theta / Tau (phospho-S232) YWHAQ Antibody catalog # A03904S232. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

14-3-3 protein theta;14-3-3 protein T-cell;14-3-3 protein tau; Protein HS1; YWHAQ

Gene Name

YWHAQ

UniProt

P27348

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human 14-3-3 θ/τ around the phosphorylation site of Serine 232

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 97% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27764 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

14-3-3 protein theta

Subcellular Location

Cytoplasm. In neurons, axonally transported to the nerve terminals.

Protein Name

14-3-3 protein theta

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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