Anti-Actin-related protein 2 ACTR2 Antibody
Boster Bio Anti-Actin-related protein 2 ACTR2 Antibody catalog # A03898. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Actin-related protein 2; Actin-like protein 2; ACTR2; ARP2
Gene Name
ACTR2
UniProt
P61160
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human Arp2 (NP_005713.1) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9000076) . Seems to contact the pointed end of the daughter actin filament (PubMed:9000076) . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947) . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double- strand breaks (DSBs) (PubMed:29925947) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
44761 MW
Gene Name Synonym
Actin-related protein 2
Subcellular Location
Cytoplasm, cytoskeleton
Protein Name
Actin-related protein 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15358883 1 Vial
Lentiviral human ZNF649 sgRNA gene knockout kit - Lentiviral human ZNF649 sgRNA gene knockout kit (plasmid)
Ask
View Details 
MBS6334514-01 0.1 mL
PLA2G12A, ID (PLA2G12A, PLA2G12, Group XIIA secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase 12A) (MaxLight 405)
Ask
View Details MBS6334514-02 5x 0.1 mL
PLA2G12A, ID (PLA2G12A, PLA2G12, Group XIIA secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase 12A) (MaxLight 405)
Ask
View Details