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Anti-USP22 Antibody

Boster Bio Anti-USP22 Antibody catalog # A03887. Tested in WB, ICC/IF, Flow Cytometry, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Ubiquitin carboxyl-terminal hydrolase 22;3.4.19.12; Deubiquitinating enzyme 22; Ubiquitin thioesterase 22; Ubiquitin-specific-processing protease 22; USP22; KIAA1063, USP3L

Gene Name

USP22

UniProt

Q9UPT9

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.

Applications

WB, ICC, IF, Flow Cytometry, IP

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

59961 MW

Gene Name Synonym

Ubiquitin carboxyl-terminal hydrolase 22

Subcellular Location

Nucleus

Protein Name

Ubiquitin carboxyl-terminal hydrolase 22

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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