Anti-USP1 Antibody
Boster Bio Anti-USP1 Antibody catalog # A03881. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ubiquitin carboxyl-terminal hydrolase 1;3.4.19.12
Gene Name
USP1
UniProt
O94782
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human USP1 (NP_003359.3) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335) . Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995) . Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
88207 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Ubiquitin carboxyl-terminal hydrolase 1
Subcellular Location
Nucleus
Protein Name
Ubiquitin carboxyl-terminal hydrolase 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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