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Anti-TRPV3 Antibody

Boster Bio Anti-TRPV3 Antibody catalog # A03874. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Transient receptor potential cation channel subfamily V member 3; TrpV3; Vanilloid receptor-like 3; VRL-3; TRPV3

Gene Name

TRPV3

UniProt

Q8NET8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human TRPV3.

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion (at protein level) . Expressed in the keratinocyte layers of the outer root sheath and, to lesser extent, to the matrix of the hair follicles (at protein level) .

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

90636 MW

Gene Name Synonym

Transient receptor potential cation channel subfamily V member 3

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Transient receptor potential cation channel subfamily V member 3

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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