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Anti-TEFF2 TMEFF2 Antibody

Boster Bio Anti-TEFF2 TMEFF2 Antibody catalog # A03846. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tomoregulin-2; TR-2; Hyperplastic polyposis protein 1; Transmembrane protein with EGF-like and two follistatin-like domains; TMEFF2; HPP1, TENB2, TPEF; UNQ178/PRO204

Gene Name

TMEFF2

UniProt

Q9UIK5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level) . Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate.

Applications

WB, ELISA

Purification

TEFF2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

41428 MW

Gene Name Synonym

Tomoregulin-2

Subcellular Location

Isoform 1: Membrane ; Single- pass type I membrane protein .

Protein Name

Tomoregulin-2

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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