Anti-DOCK2 Antibody
Boster Bio Anti-DOCK2 Antibody catalog # A03836. Tested in WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Dedicator of cytokinesis protein 2; DOCK2; KIAA0209
Gene Name
DOCK2
UniProt
Q92608
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding Human DOCK2.
Clonality
Polyclonal
Tissue Specificity
Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
211948 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Dedicator of cytokinesis protein 2
Subcellular Location
Endomembrane system
Protein Name
Dedicator of cytokinesis protein 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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