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Anti-Protein disulfide-isomerase A6 PDIA6 Antibody

Boster Bio Anti-Protein disulfide-isomerase A6 PDIA6 Antibody catalog # A03813. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein disulfide-isomerase A6;5.3.4.1

Gene Name

PDIA6

UniProt

Q15084

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human PDIA6.

Clonality

Polyclonal

Tissue Specificity

Expressed in platelets (at protein level) .

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115) . Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390) . May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390) . Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

48121 MW

Gene Name Synonym

Protein disulfide-isomerase A6

Subcellular Location

Endoplasmic reticulum lumen

Protein Name

Protein disulfide-isomerase A6

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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