Anti-Protein disulfide-isomerase A6 PDIA6 Antibody
Boster Bio Anti-Protein disulfide-isomerase A6 PDIA6 Antibody catalog # A03813. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Protein disulfide-isomerase A6;5.3.4.1
Gene Name
PDIA6
UniProt
Q15084
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human PDIA6.
Clonality
Polyclonal
Tissue Specificity
Expressed in platelets (at protein level) .
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115) . Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390) . May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390) . Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
48121 MW
Gene Name Synonym
Protein disulfide-isomerase A6
Subcellular Location
Endoplasmic reticulum lumen
Protein Name
Protein disulfide-isomerase A6
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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