Anti-IMPDH1 Antibody
Boster Bio Anti-IMPDH1 Antibody catalog # A03791. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Inosine-5'-monophosphate dehydrogenase 1
Gene Name
IMPDH1
UniProt
P20839
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human IMPDH1 (NP_899066.1) .
Clonality
Polyclonal
Tissue Specificity
IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
55406 MW
Gene Name Synonym
Inosine-5'-monophosphate dehydrogenase 1
Subcellular Location
Cytoplasm
Protein Name
Inosine-5'-monophosphate dehydrogenase 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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