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Anti-IMPDH1 Antibody

Boster Bio Anti-IMPDH1 Antibody catalog # A03791. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Inosine-5'-monophosphate dehydrogenase 1

Gene Name

IMPDH1

UniProt

P20839

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IMPDH1 (NP_899066.1) .

Clonality

Polyclonal

Tissue Specificity

IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

55406 MW

Gene Name Synonym

Inosine-5'-monophosphate dehydrogenase 1

Subcellular Location

Cytoplasm

Protein Name

Inosine-5'-monophosphate dehydrogenase 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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