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Anti-TCL1A Antibody (Center)

Boster Bio Anti-TCL1A Antibody (Center) (Catalog # A03713-1) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.

Synonyms

T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1A, TCL1

Gene Name

TCL1A

UniProt

P56279

Host

Rabbit

Reactivity

Human

Immunogen

This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.

Clonality

Polyclonal

Tissue Specificity

Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation

Applications

Flow Cytometry, WB

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

13460 Da

Subcellular Location

Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Note=Microsomal fraction

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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