What is the catalog number for Anti-WAPL Antibody?

The catalog number for Anti-WAPL Antibody is A03684.

What sizes are available for Anti-WAPL Antibody?

Anti-WAPL Antibody is available in the following size(s): 0.1 mg.

Is Anti-WAPL Antibody in stock?

Anti-WAPL Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-WAPL Antibody?

The safety data sheet for Anti-WAPL Antibody is available here: https://www.bosterbio.com/msds?sku=A03684.

Anti-WAPL Antibody

Boster Bio Anti-WAPL Antibody (Catalog # A03684) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1) . It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1) (1,2,4) . WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits (3,4) . WAPL is a new regulator of the development and metastasis of cancerous tissue (4,5) .

Synonyms

FOE, WAPL, KIAA0261, FOE, Wings apart-like protein homolog, Friend of EBNA2 protein

Gene Name

WAPAL

UniProt

Q7Z5K2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.

Immunogen

WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL. The immunogen is located within amino acids 30 - 80 of WAPL.

Clonality

Polyclonal

Tissue Specificity

Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis, Stem Cells

Purification

WAPL antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Storage Conditions

Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

132946 MW

Gene Name Synonym

Wings apart-like homolog (Drosophila)

Subcellular Location

Isoform 2: Nucleus.

Protein Name

Wings apart-like homolog (Drosophila)

Isotype

IgG

WAPL antibody is supplied in PBS containing 0.02% sodium azide.

Frequently Asked Questions

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Anti-WAPL Antibody

Product Specifications

Background

Synonyms

Gene Name

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Observed Molecular Weight

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Frequently Asked Questions

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