Anti-ULBP2 Antibody
Boster Bio Anti-ULBP2 Antibody catalog # A03657-1. Tested in WB, IHC, ELISA. This antibody reacts with Human.
Product Specifications
Background
NKG2D is an activating cell surface receptor that is predominantly expressed on cytotoxic immune cells. NKG2D recognizes a wide range of ligands. In humans, the NKG2D ligand (NKG2DL) includes MICA, MICB, and six members of the ULBP family (ULBP1-6) (PMID: 29568297; 30813924) . ULBPs are MHC class I-related molecules (PMID: 11239445) . ULBP2 contains two Ig-like domains, the alpha-1 and alpha-2 domains characteristic of the MHC class I family, but lacks the alpha-3 domain. It can be expressed as either a transmembrane or GPI-linked protein, or released from the cell surface (PMID: 21224393; 24614922) . ULBP2 binds and activates the NKG2D, mediating the recruitment and activation of NK cells.
Gene Name
ULBP2
UniProt
Q9BZM5
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human ULBP2 recombinant protein (Position: R27-Q221) .
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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