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Anti-ULBP2 Antibody

Boster Bio Anti-ULBP2 Antibody catalog # A03657-1. Tested in WB, IHC, ELISA. This antibody reacts with Human.

Product Specifications

Background

NKG2D is an activating cell surface receptor that is predominantly expressed on cytotoxic immune cells. NKG2D recognizes a wide range of ligands. In humans, the NKG2D ligand (NKG2DL) includes MICA, MICB, and six members of the ULBP family (ULBP1-6) (PMID: 29568297; 30813924) . ULBPs are MHC class I-related molecules (PMID: 11239445) . ULBP2 contains two Ig-like domains, the alpha-1 and alpha-2 domains characteristic of the MHC class I family, but lacks the alpha-3 domain. It can be expressed as either a transmembrane or GPI-linked protein, or released from the cell surface (PMID: 21224393; 24614922) . ULBP2 binds and activates the NKG2D, mediating the recruitment and activation of NK cells.

Gene Name

ULBP2

UniProt

Q9BZM5

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human ULBP2 recombinant protein (Position: R27-Q221) .

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03657-1

Product MSDS

https://www.bosterbio.com/datasheet?sku=A03657-1

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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