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Anti-Methionine aminopeptidase 2 METAP2 Antibody

Boster Bio Anti-Methionine aminopeptidase 2 METAP2 Antibody catalog # A03648. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Methionine aminopeptidase 2

Gene Name

METAP2

UniProt

P50579

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human METAP2 (NP_006829.1) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) . The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N- terminal Met-Val and Met-Thr sequences in vivo.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

52892 MW

Applications Notes

WB: 1:200-1:2000

Gene Name Synonym

Methionine aminopeptidase 2

Subcellular Location

Cytoplasm

Protein Name

Methionine aminopeptidase 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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