Anti-PINX1 Antibody
Boster Bio Anti-PINX1 Antibody catalog # A03576. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1; PINX1; LPTL, LPTS
Gene Name
PINX1
UniProt
Q96BK5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human PINX1.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
37035 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
PIN2/TERF1-interacting telomerase inhibitor 1
Subcellular Location
Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE.
Protein Name
PIN2/TERF1-interacting telomerase inhibitor 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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