Anti-MAGEA1 (F293) Antibody
Boster Bio Anti-MAGEA1 (F293) Antibody catalog # A03570. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen; MAGEA1; MAGE1, MAGE1A
Gene Name
MAGEA1
UniProt
P43355/Q8WWH6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 280-320 of Human MAGE-1.
Clonality
Polyclonal
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
34342 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Melanoma-associated antigen 1
Subcellular Location
Cytoplasm. Nucleus.
Protein Name
Melanoma-associated antigen 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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