Anti-NHEJ1 Antibody
Boster Bio Anti-NHEJ1 Antibody catalog # A03552. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Non-homologous end-joining factor 1; Protein cernunnos; XRCC4-like factor; NHEJ1; XLF
Gene Name
NHEJ1
UniProt
Q9H9Q4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NHEJ1 (NP_079058.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V (D) J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781) . Binds DNA in a length-dependent manner (PubMed:17317666) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
33337 MW
Applications Notes
WB: 1:200-1:2000
Gene Name Synonym
Non-homologous end-joining factor 1
Subcellular Location
Nucleus
Protein Name
Non-homologous end-joining factor 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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